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Each episode of AJP Audio brings you an in-depth look at one of the articles featured in that month’s issue of The American Journal of Psychiatry, the official journal of the American Psychiatric Association. Wide-ranging interviews with article authors cover the background, rationale, main findings, and future implications of the research.

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  2. January 2026: Reduced Threat-Related Neural Efficiency: A Possible Biomarker for Pediatric Anxiety Disorders

January 2026: Reduced Threat-Related Neural Efficiency: A Possible Biomarker for Pediatric Anxiety Disorders

Jan 1, 2026

Dr. Julia Linke (University of Mainz, Germany) joins AJP Audio to discuss the use of neural efficiency, a measure of brain activity, as a potential biomarker in the treatment of children with anxiety disorder.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins the podcast to put the rest of the issue into context.

  • 00:31   Linke interview
  • 02:15   State or a trait?
  • 04:15   Neural efficiency and CBT
  • 05:22   Potential as a biomarker
  • 07:08   Patient-rated and parent-rated measures of anxiety
  • 08:16   Immediate clinical implications
  • 09:50   Limitations
  • 10:43   Future directions of research
  • 11:44   Kalin interview
  • 11:50   Linke et al.
  • 15:16   Mallard et al.
  • 18:11   Naples et al.
  • 21:44   Mac Giollabhui et al.

Transcript

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