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Each episode of AJP Audio brings you an in-depth look at one of the articles featured in that month’s issue of The American Journal of Psychiatry, the official journal of the American Psychiatric Association. Wide-ranging interviews with article authors cover the background, rationale, main findings, and future implications of the research.

Jul 1, 2019

Executive Editor Michael Roy speaks with Roscoe O. Brady, Jr., M.D., Ph.D., and Mark A. Halko, Ph.D., about their research on identifying and treating a network of connectivity in the brain corresponding to negative symptom severity in schizophrenia.

  • The difference between positive and negative symptoms in psychosis, and why the symptoms are important [2:39]
  • Identifying the treating the underlying circuitry of negative symptoms in the brain [6:25]
  • Discussion of the results of the study [10:20]
  • Symptom severity and the link between the prefrontal cortex and cerebellum [12:27]
  • Aspects of the study that are relevant for researchers, clinicians, and other mental health professionals [20:40]
  • What's next in this line of research and clinical care [25:40]

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